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Timothy Fredsgaard-Jones
DPhil Student
DPhil Student & MRC Clinical Research Training Fellow
I am a clinical research fellow working on tuberculosis immunology and vaccine platforms in Professor McShane's Group.
I am an MRC Clinical Research Training Fellow, and am completing a DPhil in Clinical Medicine under the supervision of Professor McShane, Dr Jethro Johnson (Kennedy Institue), Professor Marc Lipman (UCL) and Dr David Lowe (UCL). I will be recruiting individuals with recent exposure to Mycobacterium tuberculosis and will characterise the early pulmonary and systemic immune response. I will also explore the respiratory microbiome in these individuals and investigate the impact of the microbiome on disease states in TB.
I completed my medical training at the University of Cambridge and University College London, and have worked as a medical and infection doctor in London, Glasgow and Oxford. I have conducted research in Tuberculosis, HIV, COVID-19 and enteral parasites both in the UK and Malawi. I have a particular interest in Tuberculosis and Tropical Medicine, and have completed the DTMH and an MSc at the London School of Hygiene and Tropical Medicine. I have worked as a research fellow with the Infectious Diseases department at the Royal Free Hospital London, and joined the McShane group while working as an NIHR Academic Clinical Fellow in Infectious Diseases/GIM in the Thames Valley Deanery. While an ACF I was lead clinician for two BCG challenge studies.
I currently organise the infection placements for Oxford University undergraduate medical students, and am also a tutor on the Oxford University LabMed course.
Recent publications
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Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study
Journal article
Jackson S. et al, (2024), The Lancet Microbe
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Antimicrobial resistance in bacterial wound, skin, soft tissue and surgical site infections in Central, Eastern, Southern and Western Africa: A systematic review and meta-analysis
Journal article
Monk EJM. et al, (2024), PLOS Global Public Health, 4, e0003077 - e0003077
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An assessment of the downstream implications of blood culture collection and transit
Journal article
Davies PJB. et al, (2023), European Journal of Clinical Microbiology & Infectious Diseases
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Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial
Journal article
Abani O. et al, (2023), The Lancet, 401, 1499 - 1507
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Healthy volunteer symptom profile following research bronchoscopy
Conference paper
Morrison H. et al, (2023), EUROPEAN RESPIRATORY JOURNAL, 62