Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study

Jackson S., Marshall JL., Mawer A., Lopez-Ramon R., Harris SA., Satti I., Hughes E., Preston-Jones H., Cabrera Puig I., Longet S., Tipton T., Laidlaw S., Doherty RP., Morrison H., Mitchell R., Tanner R., Ateere A., Stylianou E., Wu M-S., Fredsgaard-Jones TPW., Breuer J., Rapeport G., Ferreira VM., Gleeson F., Pollard AJ., Carroll M., Catchpole A., Chiu C., McShane H., Alparaque M., Anid L., Barnes E., Benamore R., Bharti N., Patel B., Burns A., Byard N., Conway O., Cooper C., Crowther C., Dunachie SJ., Johnstone T., Jose J., Luciw M., Mujadidi Y., Nehiweze A., Nyamunda S., Orobiyi-Rieba M., Parvelikudy B., Platt A., Pswarayi D., Quaddy J., Samuel BE., Sette A., Sodipo V., Srijith P., Stone H., Turner C., Valmores MA., Voaides A., Vuddamalay G.

DOI

10.1016/s2666-5247(24)00025-9

Type

Journal article

Journal

The Lancet Microbe

Publisher

Elsevier BV

Publication Date

05/2024

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