Senior Research Assistant
I obtained a BSc (Hons) in Biology from the University of Bath in 2006 and have been a member of the Tuberculosis research group at the Jenner Institute since 2009.
My main role is managing the laboratory side of the tuberculosis clinical trials; preparing for new trials, processing samples from trial volunteers and carrying out immunological assays to assess the response to candidate vaccines. Current trials are investigating the immune response to aerosol BCG and we are developing controlled human infection models using intradermal and aerosol BCG as surrogates for M. tb infection.
I also work on exploratory projects within the group and train students and new starters on laboratory techniques.
Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial
Folegatti PM. et al, (2020), The Lancet, 396, 467 - 478
Factors affecting the species of Campylobacter colonizing chickens reared for meat.
Babacan O. et al, (2020), Journal of applied microbiology
A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime - MVA85A boost in healthy UK adults.
Wilkie M. et al, (2020), Vaccine, 38, 779 - 789
Cytomegalovirus infection is a risk factor for tuberculosis disease in infants.
Müller J. et al, (2019), JCI insight, 4
Alternate aerosol and systemic immunisation with a recombinant viral vector for tuberculosis, MVA85A: A phase I randomised controlled trial.
Manjaly Thomas Z-R. et al, (2019), PLoS medicine, 16