Stephanie Harris
Senior Research Assistant
I obtained a BSc (Hons) in Biology from the University of Bath in 2006 and have been a member of the Tuberculosis research group at the Jenner Institute since 2009.
My main role is managing the laboratory side of the tuberculosis clinical trials; preparing for new trials, processing samples from trial volunteers and carrying out immunological assays to assess the response to candidate vaccines. Current trials are investigating the immune response to aerosol BCG and we are developing controlled human infection models using intradermal and aerosol BCG as surrogates for M. tb infection.
I also work on exploratory projects within the group and train students and new starters on laboratory techniques.
Recent publications
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Evaluation of immune profiles associated with control of mycobacterial growth in systemic lupus erythematosus (SLE) patients.
Journal article
Ongarj J. et al, (2024), Tuberculosis (Edinburgh, Scotland), 148
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Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial
Journal article
Satti I. et al, (2024), The Lancet Infectious Diseases, 24, 909 - 921
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Safety, tolerability, viral kinetics, and immune correlates of protection in healthy, seropositive UK adults inoculated with SARS-CoV-2: a single-centre, open-label, phase 1 controlled human infection study
Journal article
Jackson S. et al, (2024), The Lancet Microbe
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Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants
Journal article
Satti I. et al, (2022), Nature Communications, 13
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Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study.
Journal article
Wilkie M. et al, (2022), Scientific reports, 12