Research groups
Dr César López-Camacho
Senior Researcher in Vaccinology
- Liverstage Malaria Group
Antigen design and vaccine development for infectious diseases
PROFILE
César López-Camacho holds a PhD in Molecular Biology from the University of Manchester, United Kingdom, and has held four postdoctoral positions in molecular biology, fidelity of gene expression, and vaccinology at UMASS Medical School-USA, University of Vermont College of Medicine-USA and the Jenner Institute at University of Oxford, respectively. He is currently a Senior Researcher working with Prof Adrian Hill at the Jenner Institute in the Liver-stage Malaria Group.
During the coronavirus pandemic, his scientific activity encompassed the design and protein production of SARS-CoV-2 antigens to be utilised as diagnostic tools, for coronavirus research applications and for the exploration of the immune responses in COVID-19 convalescent individuals in the Laboratory of Prof. Gavin Screaton. He is part of the COVID-19 Outbreak Expert Database for the UK parliament; part of the National COVID Testing Scientific Advisory Panel and joined the College of Experts to Support the Global Effort on COVID-19 (GECO), as grant applications reviewer.
In the pre-COVID era, his main research aims are the immunopathogenesis of Dengue virus and vaccine development of novel antigen candidates, to induce specific anti-flavivirus antibody responses against functional and conformational epitopes. Doctor López-Camacho joined the Jenner Institute in 2014 as a postdoctoral researcher in Reyes-Sandoval’s group and worked on vaccine development for several arboviruses (Zika, Dengue, Chikungunya and Mayaro viruses). During this time he extensively published scientific work, both as first author and as co-author, in relation to arboviral, parasitic (malaria and chagas disease) and Papillomavirus vaccine developments.
In terms of intellectual property activities, he is an inventor and collaborator in vaccine-related Patents.
Key publications
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Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors
Journal article
López-Camacho C. et al, (2018), Nature Communications, 9
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Immunogenicity and Efficacy of Zika Virus Envelope Domain III in DNA, Protein, and ChAdOx1 Adenoviral-Vectored Vaccines.
Journal article
López-Camacho C. et al, (2020), Vaccines, 8
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Assessment of Immunogenicity and Neutralisation Efficacy of Viral-Vectored Vaccines Against Chikungunya Virus
Journal article
López-Camacho C. et al, (2019), Viruses, 11, 322 - 322
Recent publications
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McNaughton A. et al, (2021)
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Journal article
Dejnirattisai W. et al, (2021), Cell, 184, 2939 - 2954.e9
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Journal article
Zhou D. et al, (2021), Cell, 184, 2348 - 2361.e6
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Journal article
Supasa P. et al, (2021), Cell, 184, 2201 - 2211.e7
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Journal article
Dejnirattisai W. et al, (2021), Cell, 184, 2183 - 2200.e22