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Nanotechnology based therapeutics for lung disease
Doroudian M. et al, (2019), Thorax, 74, 965 - 976
Aerosolized nanodrug delivery system to inhibit Macrophage migration inhibitory factor in order to treat lung cancer
Doroudian M. et al, (2017), IRISH JOURNAL OF MEDICAL SCIENCE, 186, S423 - S423
Macrophage Migration Inhibitory Factor enhances Pseudomonas aeruginosa biofilms, a potential novel therapeutic for Cystic Fibrosis Patients
O'Neill A. et al, (2017), IRISH JOURNAL OF MEDICAL SCIENCE, 186, S420 - S421
Inosine Can Increase DNA′s Susceptibility to Photo‐oxidation by a RuIIComplex due to Structural Change in the Minor Groove
Keane PM. et al, (2017), Chemistry – A European Journal, 23, 10344 - 10351
The development of ruthenium(ii) polypyridyl complexes and conjugates forin vitrocellular andin vivoapplications
Poynton FE. et al, (2017), Chemical Society Reviews, 46, 7706 - 7756
Direct observation by time-resolved infrared spectroscopy of the bright and the dark excited states of the [Ru(phen)2(dppz)]2+ light-switch compound in solution and when bound to DNA
Poynton FE. et al, (2016), Chemical Science, 7, 3075 - 3084
Monitoring one-electron photo-oxidation of guanine in DNA crystals using ultrafast infrared spectroscopy
Hall JP. et al, (2015), Nature Chemistry, 7, 961 - 967
Reversal of a Single Base-Pair Step Controls Guanine Photo-Oxidation by an Intercalating Ruthenium(II) Dipyridophenazine Complex
Keane PM. et al, (2015), Angewandte Chemie International Edition, 54, 8364 - 8368
Detailed Biological Profiling of a Photoactivated and Apoptosis Inducing pdppz Ruthenium(II) Polypyridyl Complex in Cancer Cells
Cloonan SM. et al, (2015), Journal of Medicinal Chemistry, 58, 4494 - 4505
Enantiomeric Conformation Controls Rate and Yield of Photoinduced Electron Transfer in DNA Sensitized by Ru(II) Dipyridophenazine Complexes
Keane PM. et al, (2015), The Journal of Physical Chemistry Letters, 6, 734 - 738
Monitoring guanine photo-oxidation by enantiomerically resolved Ru(ii) dipyridophenazine complexes using inosine-substituted oligonucleotides
Keane PM. et al, (2015), Faraday Discussions, 185, 455 - 469
Unexpected DNA binding properties with correlated downstream biological applications in mono vs. bis-1,8-naphthalimide Ru(ii)-polypyridyl conjugates
Ryan GJ. et al, (2015), Dalton Transactions, 44, 16332 - 16344
Synthesis, photophysical and cytotoxicity evaluations of DNA targeting agents based on 3-amino-1,8-naphthalimide derived Tröger's bases
Murphy S. et al, (2014), Organic & Biomolecular Chemistry, 12, 6610 - 6610