Colleges
Adrian Hill
Director of the Jenner Institute, Lakshmi Mittal & Family Professor of Vaccinology, Professor of Human Genetics
Vaccines for malaria and other major diseases
Adrian V. S. Hill KBE, FRCP, FRS is the Lakshmi Mittal Professor of Vaccinology and Director of the Jenner Institute at Oxford University. In 2005 he founded the Jenner Institute at Oxford, which is now one of the largest academic vaccine centres globally with clinical-stage vaccine programmes against fifteen diseases.
His current lead malaria vaccine, R21 in matrix-M adjuvant, has shown high efficacy in clinical trials in the UK and Africa (Lancet. 2021;397:1809-1818) and could be the first widely used vaccine to impact on the great disease burden of malaria in Africa.
In Q1 2020, the Jenner Institute initiated a major effort towards rapid development of a COVID-19 vaccine which in collaboration with AstraZeneca is now in world-wide pandemic deployment.
He has published over 600 research papers with 60,000 citations and co-founded several spin-off companies. He is a Fellow of the UK Academy of Medical Sciences, the Royal College of Physicians and the Royal Society.
Recent publications
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A roadmap of priority evidence gaps for the co-implementation of malaria vaccines and perennial malaria chemoprevention
Journal article
Grant J. et al, (2025), Malaria Journal, 24
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Core-shell microcapsules compatible with routine injection enable prime/boost immunization against malaria with a single shot.
Journal article
Guyon R. et al, (2025), Sci Transl Med, 17
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Identification of cross-stage, cross-species malaria CD8+ T cell antigens.
Journal article
Junqueira C. et al, (2025), Res Sq
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A phase 1/2a clinical trial to assess safety and immunogenicity of an adenoviral-vectored capsular group B meningococcal vaccine
Journal article
Dold C. et al, (2025), Science Translational Medicine, 17
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A phase 1b clinical trial to determine the safety, tolerability and immunogenicity of simian adenovirus and poxvirus vectored vaccines against Mycobacterium avium complex subspecies in patients with active Crohn's disease.
Journal article
Sanderson J. et al, (2025), EBioMedicine, 113