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Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled, phase 2b trial in children.
Natama HM. et al, (2024), The Lancet. Infectious diseases
Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial
Silk SE. et al, (2024), The Lancet Infectious Diseases, 24, 1105 - 1117
Vaccine-induced human monoclonal antibodies to PfRH5 show broadly neutralizing activity against P. falciparum clinical isolates.
Thiam LG. et al, (2024), NPJ vaccines, 9
Rational structure-guided design of a blood stage malaria vaccine immunogen presenting a single epitope from PfRH5.
Harrison TE. et al, (2024), EMBO Mol Med
Plug and play virus-like particles for the generation of anti-toxin antibodies.
Edge RJ. et al, (2024), Toxicon: X, 23
Synergistic blockade of TIGIT and PD-L1 increases type-1 inflammation and improves parasite control during murine blood-stage Plasmodium yoelii non-lethal infection.
Dookie RS. et al, (2024), Infection and immunity
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Wang LT. et al, (2024), Cell
Preclinical development of a stabilized RH5 virus-like particle vaccine that induces improved antimalarial antibodies.
King LDW. et al, (2024), Cell reports. Medicine, 5
Structure-guided design of aPlasmodium vivaxDuffy binding protein-based vaccine immunogen
Barber NM. et al, (2024)
Evaluation of the precision of the Plasmodium knowlesi growth inhibition assay for Plasmodium vivax Duffy-binding protein-based malaria vaccine development
Mertens JE. et al, (2024), Vaccine, 42, 3621 - 3629
Analyses of human vaccine-specific circulating and bone marrow-resident B cell populations reveal benefit of delayed vaccine booster dosing with blood-stage malaria antigens
Barrett JR. et al, (2024), Frontiers in Immunology, 14
PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial
Martinez FJ. et al, (2024), npj Vaccines, 9
Adeno-associated viral vectored delivery of monoclonal antibody genes against blood-stage malaria
Bardelli M. et al, (2024), HUMAN GENE THERAPY, 35, A130 - A131
Cross reactive responses between filovirus species amongst a cohort of Ebolavirus Zaire survivors in Guinea, West Africa
Jiwa Y. et al, (2024), EUROPEAN JOURNAL OF IMMUNOLOGY, 54, 82 - 82
The PfRCR complex bridges malaria parasite and erythrocyte during invasion.
Farrell B. et al, (2023), Nature