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Safety of a controlled human infection model of tuberculosis with aerosolised, live-attenuated Mycobacterium bovis BCG versus intradermal BCG in BCG-naive adults in the UK: a dose-escalation, randomised, controlled, phase 1 trial
Journal article
Satti I. et al, (2024), The Lancet Infectious Diseases
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Journal article
Ma J. et al, (2024), Proceedings of the National Academy of Sciences of the United States of America, 121
Revaccination with BCG: does it work?
Journal article
McShane H., (2024), The Lancet. Infectious diseases
Optimising the vaccine strategy of BCG, ChAdOx1 85A, and MVA85A for tuberculosis control.
Journal article
Wajja A. et al, (2024), The Lancet. Infectious diseases
Exploring the ethics of tuberculosis human challenge models.
Journal article
Rohrig A. et al, (2023), Journal of medical ethics
Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial.
Journal article
Wajja A. et al, (2023), The Lancet. Infectious diseases
Adopting human factors in early phase and experimental medicine research: A nested pilot study observing controlled human infection with SARS-CoV-2.
Journal article
Higham HE. et al, (2023), British journal of clinical pharmacology
Improving TB vaccine trial efficiency: A tough nut to crack.
Journal article
Mcshane H., (2023), The Journal of infectious diseases
A five-antigen Esx-5a fusion delivered as a prime-boost regimen protects against M.tb challenge.
Journal article
Stylianou E. et al, (2023), Frontiers in immunology, 14
BCG: Past, Present and Future Direction
Chapter
Morrison H. and McShane H., (2023), Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges: Focus on Leprosy, Leishmaniasis, Melioidosis and Tuberculosis, 171 - 195
Controlled human infection models in COVID-19 and tuberculosis: current progress and future challenges.
Journal article
Morrison H. et al, (2023), Frontiers in immunology, 14
Healthy volunteer symptom profile following research bronchoscopy
Conference paper
Morrison H. et al, (2023), EUROPEAN RESPIRATORY JOURNAL, 62
Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi.
Journal article
Gordon SB. et al, (2023), Wellcome Open Res, 8
The VALIDATE Network: Accelerating Vaccine Development for Tuberculosis, Leishmaniasis, Melioidosis and Leprosy
Chapter
Vermaak S. et al, (2023), Vaccines for Neglected Pathogens: Strategies, Achievements and Challenges: Focus on Leprosy, Leishmaniasis, Melioidosis and Tuberculosis, 11 - 25
Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants
Journal article
Satti I. et al, (2022), Nature Communications, 13
Functional in-vitro evaluation of the non-specific effects of BCG vaccination in a randomised controlled clinical study.
Journal article
Wilkie M. et al, (2022), Scientific reports, 12
Tuberculosis vaccines in the era of Covid-19 - what is taking us so long?
Journal article
Dockrell HM. and McShane H., (2022), EBioMedicine, 79
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults.
Journal article
Killingley B. et al, (2022), Nat Med
Challenges in Developing a Controlled Human Tuberculosis Challenge Model.
Journal article
Jackson S. and McShane H., (2022), Curr Top Microbiol Immunol