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Audio Podcasts: Jenner Institute Originals

Vaccines: From Concept to Clinic

sean-photo.jpegThis 4 part audio podcast series on "Vaccines: From Concept to Clinic" was created in partnership with Oxford Sparks and is presented by Dr Sean Elias.




Episode 1: Why vaccinate - The history and science of vaccination

why-vaccinate.jpegVaccines are arguably the most successful medical interventions in human history saving millions of lives annually and contributed significantly to the elimination of one of the world’s most deadly diseases, smallpox. In this episode we cover the origins of vaccination and the science behind how vaccines work. We also discuss how common misgivings about vaccination can lead to dangerous outbreaks of infectious disease.

Find out more and listen to the podcast.

Episode 2: Maladies & Mice - Pre-clinical vaccine development

sean-podcast-2-photo.jpegWhilst many of the world’s major diseases can be targeted by vaccines there is a drastic need for new or improved vaccines against a number of the most deadly including HIV, malaria, Tuberculosis and Influenza. In this episode we discuss why these diseases and others have been particularly difficult to target by vaccination and the approaches currently being used in the development of vaccines targeting them. Featuring guests, Lynda Coughlan and Rachel Tanner.

Find out more and listen to the podcast.

Episode 3: How clean is a clean room? Human vaccine manufacture

microdispenser.jpgVaccines, like any medicinal product, need to be manufactured at the highest standard before they are allowed to be tested in humans. Achieving such standards take time, money and careful planning. In this episode we discuss the stringent processes that take a vaccine from a preclinical stage to the clinic ready for vaccination in human subjects. Featuring guest, Emma Bolam.

Find out more and listen to the podcast.

Episode 4: Medical science needs you! Human clinical trials

concept-to-clinic-podcast.jpegTesting novel vaccines in humans is the first step on a long route to licensure. Clinical trials are long and expensive, but essential, procedures designed to confirm vaccine safety but also its effectiveness. Here we discuss clinical trial design and the important role of clinical trial volunteers with an overview of what volunteering for a clinical vaccine trial entails. Featuring guest Natalie Lella.

Find out more and listen to the podcast.



Podcast: Sandy Douglas - Going Viral

100.jpegSandy Douglas from the Jenner institute features in this Medical Sciences Division podcast on viruses, released to mark World Rabies Day.

He discusses the first rabies vaccine and his new strategy to fight rabies using an adenovirus. Other scientists from the Division talk about using viruses to understand how the brain works.




 Other Podcasts

The Slightly Scientific Podcast

In this episode, Oliver, Finley and Oscar interview Professor Sarah Gilbert, the developer of the Oxford-AstraZeneca Vaccine to learn more about how the vaccine works, how they were able to develop the vaccine in 12 months and how the vaccine will play out in this pandemic.

Podcast Here

STEM in the Gorbals

What is a vaccine? How do they work? And how do we make them? Join Jessica (14) and Annabelle (8) in conversation with Infectious Disease Expert Professor Emma Thomson (Centre for Virus Research, University of Glasgow) and Dr Sean Elias (The Jenner Institute, University of Oxford).

Recorded in Spring 2021.

Podcast Here