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The 24 - 30 April is World Immunisation Week with the focus of this year’s WHO campaign is “Close the immunisation gap”. NDM and Paediatrics spoke to Professor Calman MacLennan, Professor of Vaccine Immunology (University of Birmingham) and Jenner Investigator (Oxford), and Dr Manish Sadarangani Clinical Lecturer and Honorary Consultant in Paediatric Infectious Diseases and Immunology at The Children’s Hospital, Oxford about vaccinations and how we can “close the gap” and get more people vaccinated to prevent deadly diseases.