Iman Satti
Dr
Senior Scientist
Research
I hold BSc (Hons) and MSc in Zoology/Immunology from the University of Khartoum (Khartoum, Sudan) and PhD degree in Immunology/infection biology from Karolinska Institute (Stockholm, Sweden). I am currently a senior scientist, leading the human immunology research in the TB group.
My research focuses on identifying correlates of risk of TB in endemic areas and comprehensively characterising the host immune responses following TB vaccination and controlled human mycobacterial challenge. These studies also involve investigating human immune responses after delivery of TB vaccines via the aerosol route. I have established novel immune monitoring techniques for the evaluation of lung mucosal and systemic immune responses following both aerosol mycobacterial challenge and aerosol vaccination.
Key Publications
Recent publications
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Early mucosal responses following a randomised controlled human inhaled infection with attenuated Mycobacterium bovis BCG
Journal article
Marshall JL. et al, (2025), Nature Communications, 16
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Evaluation of immune profiles associated with control of mycobacterial growth in systemic lupus erythematosus (SLE) patients.
Journal article
Ongarj J. et al, (2024), Tuberculosis (Edinburgh, Scotland), 148
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Inhaled aerosol viral-vectored vaccines against tuberculosis.
Journal article
Stylianou E. and Satti I., (2024), Current opinion in virology, 66
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Safety and immunogenicity of ChAdOx1 85A prime followed by MVA85A boost compared with BCG revaccination among Ugandan adolescents who received BCG at birth: a randomised, open-label trial.
Journal article
Wajja A. et al, (2024), The Lancet. Infectious diseases, 24, 285 - 296
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Optimising the vaccine strategy of BCG, ChAdOx1 85A, and MVA85A for tuberculosis control
Journal article
Wajja A. et al, (2024), The Lancet Infectious Diseases, 24, e78 - e79