Anthony Brown
Research Assistant
Brief Biography:
I’ve been working with Professor Barnes since 2007 and have mainly been working on the Phase 1 clinical candidate HCV vaccine studies that have been carried out in Oxford, looking at their immunogenicity in healthy volunteers and HCV patients.
I have also been involved in the NGS work of various pathogenic viruses, particularly HCV, that has been set up in collaboration with the Welcome Trust Centre for Human Genomics.
In addition to these main roles I have been looking at the immune response to HEV in HEV exposed individuals from Cornwall and Oxford in a collaboration with Dr Harry Dalton.
Research interests:
HCV sequencing and vaccination, all aspects of HEV infection and viral sequencing
Current projects:
PEACHI vaccine study, STOP-HCV viral sequencing and host immune response to HEV infection
Recent publications
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Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 in HIV infection: a single-arm substudy of a phase 2/3 clinical trial
Journal article
Frater J. et al, (2021), The Lancet HIV, 8, e474 - e485
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Natural and vaccine-induced antibody and cellular responses against emerging SARS-CoV-2 variants of concern
Journal article
Skelly DT. et al, (2021)
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Illumina and Nanopore methods for whole genome sequencing of hepatitis B virus (HBV)
Journal article
McNaughton AL. et al, (2019), Scientific Reports, 9
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Resistance analysis of genotype 3 hepatitis C virus indicates subtypes inherently resistant to nonstructural protein 5A inhibitors
Journal article
Smith D. et al, (2019), Hepatology, 69, 1861 - 1872
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Characterization of hepatitis C virus resistance to grazoprevir reveals complex patterns of mutations following on-treatment breakthrough that are not observed at relapse
Journal article
Bonsall D. et al, (2018), Infection and Drug Resistance, Volume 11, 1119 - 1135