Detection of Vaccine-Induced Antibodies to Ebola Virus in Oral Fluid

Lambe T., Rampling T., Samuel D., Bowyer G., Ewer KJ., Venkatraman N., Edmans M., Dicks S., Hill AVS., Tedder RS., Gilbert SC.

Abstract Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.

DOI

10.1093/ofid/ofw031

Type

Journal article

Journal

Open Forum Infectious Diseases

Publisher

Oxford University Press (OUP)

Publication Date

01/01/2016

Volume

3

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