The Impact of Infant Bacille Calmette-Guérin Vaccination on the Immunogenicity of Other Vaccines: A Randomized Exploratory Study.

Maytum A., Porter D., de Whalley P., Thompson A., Plested E., Kerridge S., Liu X., Smits G., van der Klis F., Snape MD., Clutterbuck E., Pollard AJ.

The effect of the Bacille Calmette-Guérin (BCG) vaccine on the immunogenicity of separately administered serogroup C meningococcal vaccine and other vaccinations was examined in 28 infants randomized to receive BCG at age ≤7 days, at 3 months or after study completion. Immunogenicity of the serogroup C meningococcal vaccine and other routine vaccines might be improved when BCG is administered in early infancy.

DOI

10.1097/inf.0000000000004373

Type

Journal article

Journal

The Pediatric infectious disease journal

Publication Date

08/2024

Volume

43

Pages

809 - 812

Addresses

From the Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, United Kingdom.

Keywords

Humans, Meningococcal Vaccines, BCG Vaccine, Antibodies, Bacterial, Vaccination, Infant, Infant, Newborn, Female, Male, Immunogenicity, Vaccine

Permalink Original publication