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<jats:p>As shown by analysis of mice and humans bearing DOCK8-inactivating mutations, DOCK8 plays a cell-autonomous role in survival of naive CD8 T cells, LFA-1 polarization toward the immune synapse, and CD8 T cell memory and recall responses following viral infection.</jats:p>

Original publication

DOI

10.1084/jem.20110345

Type

Journal article

Journal

The Journal of Experimental Medicine

Publisher

Rockefeller University Press

Publication Date

24/10/2011

Volume

208

Pages

2305 - 2320