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<jats:title>Key Points</jats:title> <jats:p>The N-terminus of ERFE binds BMP6 with nanomolar affinity and is sufficient to inhibit BMP signaling and suppress hepcidin in vivo Anti-N-terminal ERFE antibodies prevent Epo-induced hepcidin suppression and decrease iron accumulation and anemia in thalassemic mice</jats:p>

Original publication

DOI

10.1182/blood.2019003140

Type

Journal article

Journal

Blood

Publisher

American Society of Hematology

Publication Date

03/01/2020