Clinical Trials Immunologist
I work on the Clinical Trials conducted as part of the Blood-Stage Malaria Programme lead by Professor Simon Draper.
This programme includes both Phase I safety and immunogenicity studies and Phase II controlled human malaria infection studies. My role focuses on the characterisation of human humoral and cellular immune responses to the candidate vaccines and malaria exposure against both Plasmodium falciparum and Plasmodium vivax.
Additionally, I work closely with collaborating field sites in Africa, to conduct Clinical Trials in a malaria-endemic setting.
A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates
Douglas AD. et al, (2019), Nature Communications, 10
Harmonization study between three laboratories for expression of malaria vaccine clinical trial IgG antibody ELISA data in µg/mL
Labbé GM. et al, (2019), Malaria Journal, 18
Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody
Rawlinson TA. et al, (2019), Nature Microbiology, 4, 1497 - 1507
Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens
Illingworth JJ. et al, (2019), Frontiers in Immunology, 10
Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies
Alanine DGW. et al, (2019), Cell, 178, 216 - 228.e21