Jordan Barrett

I conduct research for clinical trials as part of the Blood-Stage Malaria Programme led by Professor Simon Draper. These trials assess the safety, efficacy and immunogenicity of blood-stage malaria vaccine candidates against Plasmodium falciparum and Plasmodium vivax. For these UK-based trials, I coordinate laboratory activity, such as documentation, routine sample processing, assay development and primary immunological readouts. Additionally, I carry out exploratory serology and cellular assays for our trials and projects to investigate responses to vaccination and malaria exposure.

During the Oxford COVID-19 vaccine trial, I developed and conducted several new antibody assays, chiefly to investigate the levels of different immunoglobulin isotypes against SARS-CoV-2 in response to vaccination.

Prior to joining the group, I graduated from the University of Oxford with a degree in Molecular and Cellular Biochemistry. I undertook my Part II project in Professor Andrew McMichael's lab in the Nuffield Department of Medicine. During this project, I investigated the peptide binding properties of the MHC class II molecule, HLA-E, which has implications for preclinical HIV vaccine development.