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Cal MacLennan

Professor of vaccine immunology (University of Birmingham), Group Head / PI, Consultant Physician, Fellow and Member of congregation

My main research objective is to understand the immunological basis of protection against invasive bacterial disease with a view to prevention and treatment, focusing on communities in resource-limited settings and patients with impaired immunity. My programme at the Jenner Institute aims to combine improved understanding of naturally-acquired immunity and vaccine-induced immunity to invasive bacteria, focusing on Salmonella, with a view to the development of effective and affordable vaccines against these pathogens for use in the developing world. This work involves partnership and collaboration with sites in low-income countries and exploitation of effective and affordable vaccine technologies, such as Generalized Modules for Membrane Antigens (GMMA).