I am a Postdoctoral scientist working with Prof. Sumi Biswas in the Transmission-Blocking Malaria Vaccine (TBV) group. My research mainly focuses on the preclinical investigation of vaccine candidates against sexual- and mosquito- stages of malaria parasites Plasmodium falciparum and P. vivax. I work on protein-based vaccines, investigating not only different antigens, but also different vaccine-delivery platforms.
I obtained my BSc in Molecular Biological Sciences at the University of Pisa, and my MSc in Medical Biotechnology at the University of Siena. I then completed my PhD in Vaccine Design and Immune Responses, a Marie Curie ITN- European Industrial Doctorate between the University of Birmingham and the former Novartis Vaccine Institute for Global Health. My PhD project focused on meningococcal vaccines for Africa, based on outer membrane vesicles.
While completing my PhD, I worked as Research Assistant in the Division of Structural Biology, here at the University of Oxford; this experience gave me the opportunity to explore the world of electron microscopy.
My main interest is not limited to malaria, but spreads across all the scary and deadly pathogens out there, and how to fight them with innovative effective vaccines.
A Universal Plug-and-Display Vaccine Carrier Based on HBsAg VLP to Maximize Effective Antibody Response
Marini A. et al, (2019), Frontiers in Immunology, 10
Production and characterisation of the first human monoclonal antibodies against Plasmodium falciparum transmission blocking antigen Pfs25
Zaric M. et al, (2019), EUROPEAN JOURNAL OF IMMUNOLOGY, 49, 1683 - 1684
Combination of RTS,S and Pfs25-IMX313 Induces a Functional Antibody Response Against Malaria Infection and Transmission in Mice
Brod F. et al, (2018), Frontiers in Immunology, 9
Structural basis for recognition of the malaria vaccine candidate Pfs48/45 by a transmission blocking antibody
Lennartz F. et al, (2018), Nature Communications, 9
IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal
Develop at Discordant Rates
Schager AE. et al, (2018), mBio, 9