FGT-1 is the major glucose transporter in C. elegans and is central to aging pathways
Feng Y., Williams BG., Koumanov F., Wolstenholme AJ., Holman GD.
<jats:p>Only the FGT1A/B protein isoforms function as glucose transporters in C. elegans. Knockdown of fgt-1 RNA leads to loss of glucose transport, reduced glucose metabolism and extended lifespan. FGT-1 glucose transporters therefore play a key role in regulated glucose energy supply and lifespan.</jats:p>