Cytomegalovirus-Specific Immunoglobulin G Is Associated With Chronic Lung Disease in Children and Adolescents from Sub-Saharan Africa Living With Perinatal Human Immunodeficiency Virus.

Hameiri Bowen D., Sovershaeva E., Charlton B., Schive C., Odland J., McHugh G., Bandason T., Mayini J., Ferrand RA., Yindom L-M., Rowland-Jones SL.

In a cross-sectional study of 296 children and adolescents from Zimbabwe living with perinatal human immunodeficiency virus, individuals with the top tertile of cytomegalovirus-specific immunoglobulin G titer had an increased odds of chronic lung disease (odds ratio, 3.33; 95% confidence interval, 1.37-8.85; P = .010).

DOI

10.1093/cid/ciaa1757

Type

Journal article

Journal

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Publication Date

07/2021

Volume

73

Pages

e264 - e266

Addresses

Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.

Keywords

Humans, Cytomegalovirus, HIV, HIV Infections, Lung Diseases, Immunoglobulin G, Cross-Sectional Studies, Pregnancy, Adolescent, Child, Africa South of the Sahara, Zimbabwe, Female

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