Other Seminars

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Fri 1 Nov 2019 from 08:00 to 09:00

Surgical Grand Rounds

John Radcliffe Academic, Lecture Theatre 1, Headington OX3 9DU

Using research to change paradigms in diagnosing and managing early prostate cancer

Mr Vincent Gnanapragasam

Vincent Gnanapragasam graduated with BMedSci and MBBS degrees from Newcastle University. Following basic surgical training, he was one of the first trainees to be funded through a Cancer Research UK PhD for Clinicians. Whilst undertaking Higher Specialist Training in Urology in the North East,... Read more

Vincent Gnanapragasam graduated with BMedSci and MBBS degrees from Newcastle University. Following basic surgical training, he was one of the first trainees to be funded through a Cancer Research UK PhD for Clinicians. Whilst undertaking Higher Specialist Training in Urology in the North East, Vincent was appointed as Urology First Assistant (Clinical Lecturer) at Newcastle University in 2003. In 2004, supported by the first CRUK Clinician Scientist Fellowship given to a surgeon, Vincent established his own research group. He is currently a University Lecturer at the University of Cambridge, and Honorary Consultant Urologist at Addenbrooke’s Hospital, Cambridge. Vincent’s current research covers the full spectrum of basic science, translational, clinical and epidemiological disciplines in prostate cancer. He is CI of the TAPS study (Janssen), NIHR i4i funded CAMPROBE study and national Predict Prostate and PRIM bio-marker study. He is a member of the UK ICGC prostate group and the International Pan Prostate Cancer Collaborative and GAP 3 Active Surveillance consortium. He has developed novel more accurate prognostic prediction models for both group stratified cohorts and for individualised prediction and pioneered risk stratified pathways for active surveillance follow up. To date he has raised over £6M in research grant funding and published over 120 peer reviewed papers. His work has been cited in prostate cancer guidelines by NICE in 2019 and the European Association of Urology in 2018. In the University of Cambridge he (i) leads the University Academic Urology Group, (ii) co-leads the CRUK Cambridge Cancer Centre Urological Malignancies Programme and (iii) established and directs the Cambridge Urology Translational Research and Clinical Trials office. He holds patents and has won numerous prizes for research including the CE Alken prize, Urological Research Society Medial and a Hunterian Professorship. He is also a Visiting Professor at Anglia Ruskin University having established a Master’s research degree programme there for early career aspiring urologists.

Audience: Members of the University only

Organisers: Tarryn Ching

Fri 1 Nov 2019 from 09:15 to 10:15

MRC HIU Friday Morning Lab Meetings

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

Title TBC

Uhlig Group

Audience: Members of the University only

Organisers: Anne Farmer

Tue 5 Nov 2019 from 13:00 to 14:00

Molecular Haematology Unit, WIMM

MRC Weatherall Institute of Molecular Medicine, Seminar room, Headington OX3 9DS

Title TBC

Dr Moritz Gerstung

Audience: Members of the University only

Organisers: Liz Rose

Wed 6 Nov 2019 from 13:30 to 14:30

MRC HIU Wednesday Seminar Series

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

Title TBC

Prof. Andreas Pichlmair

Audience: Members of the University only

Organisers: Anne Farmer

Thu 7 Nov 2019 from 16:30 to 18:00

Experimental Medicine TGU Seminars

John Radcliffe Hospital - Main Building, John Radcliffe Hospital Main Building, George Pickering Education Centre Level 3 Academic Centre, Room 2B, Headington OX3 9DU, Headington OX3 9DU

Understanding Infection and Pathogenesis from the Epithelial Point of View

Dr Francesco Boccellato

Audience: Members of the University only

Organisers: Professor Holm Uhlig

Fri 8 Nov 2019 from 08:00 to 09:00

Surgical Grand Rounds

John Radcliffe Academic, Lecture Theatre 1, Headington OX3 9DU

Public-private partnerships in elective surgery

Professor Chris Lavy

Audience: Members of the University only

Organisers: Tarryn Ching

Fri 8 Nov 2019 from 09:15 to 10:15

MRC HIU Friday Morning Lab Meetings

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

Title TBC

McKeating Group

Audience: Members of the University only

Organisers: Anne Farmer

Mon 11 Nov 2019 from 11:00 to 12:00

WIMM Occasional Seminars

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Mon 11 Nov 2019 from 13:00 to 14:00

WIMM MONDAY SEMINARS

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Applying chemistry in regenerative medicine: from small molecule discovery to mechanism elucidation

Prof Angela Russell

Audience: Members of the University only

Organisers: Liz Cloke

Wed 13 Nov 2019 from 12:00 to 13:00

OPDC Seminar Series (DPAG)

Sherrington Library, off Parks Road OX1 3PT

Synaptic alterations in the indirect-pathway of the basal ganglia in experimental Parkinsonism

Jerome Baufreton

My laboratory is interested in understanding the synaptic and cellular mechanisms governing information transfer in the basal ganglia. This network is composed of a group of interconnected subcortical brain nuclei that are critical for voluntary movement, learning and motivation, and the primary... Read more

My laboratory is interested in understanding the synaptic and cellular mechanisms governing information transfer in the basal ganglia. This network is composed of a group of interconnected subcortical brain nuclei that are critical for voluntary movement, learning and motivation, and the primary site of dysfunction in motor-related disorders such as Parkinson´s disease (PD) and Huntington´s disease (HD). Our objectives are to define the principles underlying the normal and pathophysiological operation of the basal ganglia. Our hope is that this information will provide a better understanding of the molecular mechanisms contributing to PD and HD and will be useful in developing new therapeutic strategies that more effectively treat the symptoms of these disorders. We utilize multiple experimental approaches including electrophysiology (patch-clamp and extracellular multi-units recordings), calcium imaging, molecular profiling, optogenetics ex vivo and in vivo, neuronal tracing and immunohistochemistry. We combined all these approaches to decipher: 1) the role of specific neuronal subpopulations in motor control, 2) synaptic transmission and plasticity of GABAergic and glutamatergic synapses of the basal ganglia network, 3) the cellular and molecular mechanisms of deep brain stimulation of the subthalamic nucleus (STN-DBS). Our research is supported by the Agence National de la Recherche, the French Parkinson’s disease association and la Fondation de France.

Audience: Members of the University only

Organisers: Professor Richard Wade-Martins

Thu 14 Nov 2019 from 11:00 to 12:00

Ludwig Institute Seminar Series

NDM Building, (TDI) seminar room, Headington OX3 7FZ

'Tumor whole-genomes shed light into mutational processes and cancer vulnerabilities'

Professor Nuria Lopez-Bigas

Audience: Members of the University only

Organisers: Alexandra Ward

Fri 15 Nov 2019 from 09:15 to 10:15

MRC HIU Friday Morning Lab Meetings

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

Title TBC

Dr Emily Thornton

Audience: Members of the University only

Organisers: Anne Farmer

Mon 18 Nov 2019 from 13:00 to 14:00

WIMM MONDAY SEMINARS

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Using single cell RNA sequencing to investigate mechanisms of liver fibrosis and regeneration

Prof Neil Henderson

Audience: Members of the University only

Organisers: Liz Cloke

Tue 19 Nov 2019 from 13:00 to 14:00

Molecular Haematology Unit, WIMM

MRC Weatherall Institute of Molecular Medicine, Seminar room, Headington OX3 9DS

Title TBC

Professor Neil Brockdorff

Audience: Members of the University only

Organisers: Liz Rose

Wed 20 Nov 2019 from 14:30 to 15:30

MRC HIU Wednesday Seminar Series

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

Title TBC

Professor Mala Maini

Audience: Members of the University only

Organisers: Anne Farmer

Thu 21 Nov 2019 from 13:30 to 14:30

WIMM Occasional Seminars

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

VIVA - The regulation of zeta-globin

Dr. Andrew King

Audience: Members of the University only

Organisers: Liz Rose

Fri 22 Nov 2019 from 09:15 to 10:15

MRC HIU Friday Morning Lab Meetings

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

Title TBC

Cerundolo Group

Audience: Members of the University only

Organisers: Anne Farmer

Mon 25 Nov 2019 from 13:00 to 14:00

WIMM MONDAY SEMINARS

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Using genetic association to understand human biology

Professor Gil McVean

Patterns of genetic association have revealed much about the biology underlying human traits and complex diseases. But how can we use such information systematically to learn about the processes - at molecular, cellular and tissue levels - that modulate risk? I will discuss some challenges,... Read more

Patterns of genetic association have revealed much about the biology underlying human traits and complex diseases. But how can we use such information systematically to learn about the processes - at molecular, cellular and tissue levels - that modulate risk? I will discuss some challenges, approaches, and solutions to the problems of integrating and interpreting data on such a vast scale. And how such information can be applied to diverse problems ranging from therapeutic target identification to quantifying individual risk.

Audience: Members of the University only

Organisers: Liz Cloke

Tue 26 Nov 2019 from 13:00 to 14:00

Molecular Haematology Unit, WIMM

MRC Weatherall Institute of Molecular Medicine, Seminar room, Headington OX3 9DS

Floor meeting - 2 groups will give an update on the research work in their laboratory

Audience: Members of the University only

Organisers: Liz Rose

Fri 29 Nov 2019 from 09:15 to 10:15

MRC HIU Friday Morning Lab Meetings

MRC Weatherall Institute of Molecular Medicine, WIMM Seminar Room, Headington OX3 9DS

Title TBC

McMichael Group

Audience: Members of the University only

Organisers: Anne Farmer