Audio Podcasts

Vaccines: From Concept to Clinic

Sean photo

This audio podcast series on "Vaccines: From Concept to Clinic - Why Vaccinate?" was created in partnership with Oxford Sparks and is presented by Dr Sean Elias.



Episode 1: Why vaccinate - The history and science of vaccination

Why vaccinate?

Vaccines are arguably the most successful medical interventions in human history saving millions of lives annually and contributed significantly to the elimination of one of the world’s most deadly diseases, smallpox. In this episode we cover the origins of vaccination and the science behind how vaccines work. We also discuss how common misgivings about vaccination can lead to dangerous outbreaks of infectious disease.

Find out more and listen to the podcast.


Episode 2: Maladies & Mice - Pre-clinical vaccine development

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Whilst many of the world’s major diseases can be targeted by vaccines there is a drastic need for new or improved vaccines against a number of the most deadly including HIV, malaria, Tuberculosis and Influenza. In this episode we discuss why these diseases and others have been particularly difficult to target by vaccination and the approaches currently being used in the development of vaccines targeting them. Featuring guests, Lynda Coughlan and Rachel Tanner.

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Episode 3: How clean is a clean room? Human vaccine manufacture


Vaccines, like any medicinal product, need to be manufactured at the highest standard before they are allowed to be tested in humans. Achieving such standards take time, money and careful planning. In this episode we discuss the stringent processes that take a vaccine from a preclinical stage to the clinic ready for vaccination in human subjects. Featuring guest, Emma Bolam.

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Episode 4: Medical science needs you! Human clinical trials

Concept to clinic podcast

Testing novel vaccines in humans is the first step on a long route to licensure. Clinical trials are long and expensive, but essential, procedures designed to confirm vaccine safety but also its effectiveness. Here we discuss clinical trial design and the important role of clinical trial volunteers with an overview of what volunteering for a clinical vaccine trial entails. Featuring guest Natalie Lella.

Find out more and listen to the podcast.


Podcast: Sandy Douglas - Going Viral


Sandy Douglas from the Jenner institute features in this Medical Sciences Division podcast on viruses, released to mark World Rabies Day.

He discusses the first rabies vaccine and his new strategy to fight rabies using an adenovirus. Other scientists from the Division talk about using viruses to understand how the brain works.

Video Podcasts

A selection of podcasts and video clips created by The Jenner Institute or byThe Nuffield Department of Medicine featuring Jenner Principal Investigators.

Jenner Institute podcast.



Sarah Gilbert podcast.



Developing effective and equitable global health systems podcast.

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Vaccines and Infectious Disease - Open weeks 2015 podcast.

youtube podcast 1


All researcher podcasts