Other Seminars

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Mon 7 Aug 2017 from 12:00 to 13:00

Kennedy Institute Seminars

Kennedy Institute of Rheumatology, Bernard Sunley Lecture Theatre, Headington OX3 7LF

Single cell genomics:  tools for computational analysis with application to innate immune response to HIV-1 infection

Nir Yosef

Nir Yosef is Assistant Professor at the Department of Electrical Engineering & Computer Science and a member of the Center for Computational Biology at UC Berkeley. The overarching goal of his group’s research is to utilize high-throughput genomic data sets, mostly based on DNA sequencing, in... Read more

Nir Yosef is Assistant Professor at the Department of Electrical Engineering & Computer Science and a member of the Center for Computational Biology at UC Berkeley. The overarching goal of his group’s research is to utilize high-throughput genomic data sets, mostly based on DNA sequencing, in order to build models that explain how gene expression is regulated.  They have special interest in immune cells, covering various aspects of their biology, such as their differentiation, stability / plasticity, and response to acute stimulation.

Audience: Members of the University only

Organisers: Gintare Kolesnikovaite

Tue 8 Aug 2017 from 16:00 to 17:00

OPDC Seminar Series (DPAG)

Le Gros Clark Building, Lecture Theatre, Le Gros Clark Building, DPAG, off South Parks Road OX1 3QX

Inflammation & Neurodegeneration: a Role for Toll-like Receptors

Kathleen Maguire-Zeiss

Dr. Maguire-Zeiss' laboratory at Georgtown University aims to understand the molecular mechanisms involved in progressive neurodegenerative diseases like Parkinson's disease and HAND. The laboratory focuses on glial-directed innate immune responses and the effect of inflammation on neuronal health... Read more

Dr. Maguire-Zeiss' laboratory at Georgtown University aims to understand the molecular mechanisms involved in progressive neurodegenerative diseases like Parkinson's disease and HAND. The laboratory focuses on glial-directed innate immune responses and the effect of inflammation on neuronal health and function. By investigating how glial cells respond to chemokines/cytokines and misfolded proteins, specific signaling pathways are identified and novel therapeutics are subsequently identified and tested. For example, the Maguire-Zeiss lab demonstrated that the Parkinson's disease relevant protein, misfolded alpha-synuclein, increases oxidative stress and alters neuronal membrane conductance. This group also demonstrated that this pathologic protein directly interacts with toll-like receptors on microglia inciting a proinflammatory response in these cells. Importantly, toll-like receptor antagonists attenuate this inflammatory response. Using primary cultures, acute brain slices, and mouse models the Maguire-Zeiss lab is helping to decipher the molecular events important for the pathogenesis of disorders like Parkinson's disease and HAND in an effort to discover novel therapeutic approaches for these debilitating diseases. https://neuro.georgetown.edu/maguire-zeiss

Audience: Members of the University only

Thu 10 Aug 2017 from 13:00 to 14:00

Kennedy Institute Seminars

Kennedy Institute of Rheumatology, Bernard Sunley Lecture Theatre, Headington OX3 7LF

Structured illumination microscopy for super-resolution live cell imaging

Prof Dong Li

Audience: Members of the University only

Organisers: Gintare Kolesnikovaite

Fri 11 Aug 2017 from 15:00 to 16:00

SGC Seminars

NDM Building, TDI Basement seminar room, Headington OX3 7FZ

Identifying tomorrow’s hepatocellular carcinoma patients’

Dr Rajarshi Banerjee

Short Bio: Rajarshi has pioneered quantitative liver imaging for clinical use, and is founder and Chief Executive Officer of Perspectum Diagnostics. He qualified in medicine from Oxford in 2002, and trained as a physician in London and Oxford, where he still works as an Honorary Consultant... Read more

Short Bio: Rajarshi has pioneered quantitative liver imaging for clinical use, and is founder and Chief Executive Officer of Perspectum Diagnostics. He qualified in medicine from Oxford in 2002, and trained as a physician in London and Oxford, where he still works as an Honorary Consultant Physician. His medical research work in non-invasive tissue characterisation and extensive experience in running clinical trials whilst working in multidisciplinary scientific teams to develop applications for cutting edge imaging technology for the assessment of liver disease and liver cancer.

Audience: Public

Organisers: Natsumi Astley

Fri 18 Aug 2017 from 12:00 to 13:00

Jenner Seminars

Richard Doll Building, Lecture Theatre, Old Road Campus OX3 7LF

Wed 30 Aug 2017 from 12:30 to 13:30

WIMM Occasional Seminars

MRC Weatherall Institute of Molecular Medicine, Seminar Room, Headington OX3 9DS

Identification of a targetable EGFR-associated tumor-initiating program in breast cancer using single cell genomics

Prof Jiannis Ragoussis

Audience: Members of the University only

Organisers: Penny Berry

Please note that if you require further details, the contact is Sam Oats, not Penny Berry (aharris.lab@imm.ox.ac.uk).