Current Vacancies  

Postdoctoral Research Scientist in Proteomics/Immunopeptidomics

Applications to be received by 12pm on Wednesday 25th of October 2017

Grade 7: £31,604 - £38,833 p.a.

 We are seeking an enthusiastic Postdoctoral Research Scientist in Proteomics/Immunopeptidomics to join a CRUK Centers Network Accelerator Award that has been established between the University of Oxford, the University of Southampton and the La Jolla Institute for Allergy and Immunology, US. The programme aims to understand the processes of tumour recognition by analysing the mutanome, transcriptome and immunopeptidome of Lung cancer, Oesophageal cancer and Melanoma.

In your role as Postdoctoral Research Scientist in Proteomics/Immunopeptidomics, you will join a research programme that aims to decipher the molecular architecture of immune responses directly in tumour tissue. Your specific project will characterise the immunopeptidomes of individual patients by LC-MS/MS and analyse tumour-specific antigens in larger patient cohorts. Bench science, chromatographic and mass spectrometry workflows will be an integral part of the project.

You will have the ability to work as an independent researcher. You will join the immunopeptidomics team of Dr Nicola Ternette at the Jenner Institute and will work closely with the TDI Mass Spectrometry Laboratory. You will hold a relevant PhD (or be near completion) in quantitative biology, biochemistry or a related subject. Preference will be given to candidates with a working knowledge of proteomics. A research background in cancer research and/or immunology are a desirable prerequisite for this position.

The Postdoctoral Research Scientist in Proteomics/Immunopeptidomics role requires a basic knowledge of immunology and/or cancer pathways. The ability to communicate results clearly and effectively and to discuss scientific ideas both within the work environment and the consortium is essential.

Applications for this vacancy are to be made online. You will be required to upload a CV and supporting statement as part of your online application.

The initial appointment is for 2 years, with the possibility of additional 2 years funding.

Only applications received by 12.00 noon on 25 October 2017 will be considered.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here: www.ox.ac.uk/about/jobs/preemploymentscreening

Contact: HR Officer - Recruitment (01865 617971)

To view a Job Description and apply

Postdoctoral Research Scientist - Malaria Biology and Vaccine Development

Applications to be received by 12pm on Wednesday 25th of October 2017

Grade 7: £31,604 - £38,833 p.a.

Applications are invited for a Postdoctoral Research Scientist, Malaria Biology and Vaccine Development at the Jenner Institute located at the Centre for Cellular and Molecular Physiology, Wellcome Trust Centre for Human Genetics.

Our research seeks to develop new antibody-inducing vaccines, with projects focused upon the sporozoite stage of the malaria parasite and upon rabies. Recent work has been successful in advancing candidates against both diseases into clinical trials, and in generating high-impact publications. We aim to foster scientific excellence within an open and free-thinking environment.

You will participate in the research programme led by Dr Sandy Douglas to identify and characterise mechanisms of hepatocyte invasion by malaria sporozoites and to develop vaccine approaches to block this invasion. The project will use genetic (CRISPR-Cas9) and biochemical approaches to identify such ligand-receptor interactions. The role will offer an excellent opportunity for you to obtain and publish high-impact results while developing your skills in a rigorous but supportive environment. Simultaneously, you will have a strong chance of seeing your efforts achieve ‘real world’ impact via translation into novel vaccines.

You will have a PhD (or be in the process of completing) in a relevant area such as parasitology, immunology or another related field with an outstanding academic track record/evidence of potential. You will have excellent organisational and interpersonal skills with ability to analyse or research complex issues, interpret scientific data and write factual reports. You should also have experience of sterile cell culture techniques and basic molecular biology skills (PCR and plasmid cloning).

The post is fixed-term for 2 years in the first instance and funding provided by European Union.

You will be required to upload a CV and supporting statement as part of your online application.

Only applications received before 12.00 midday on Wednesday 25 October 2017 will be considered. Please quote reference 131212 on all correspondence. Interviews will be held on Wednesday 1 November 2017.

Please note that the University of Oxford's retirement policy is changing. With effect from October 1 2017, all employees at Grade 8 and above will have a retirement age of 68, and all employees at Grades 6 and 7 will no longer have a set retirement age. Further details are available at: www.ox.ac.uk/about/jobs/preemploymentscreening.

Contact: Sarah Hickin (01865 287507)

To view a Job Description and apply

Postdoctoral Research Scientist - Protein and Antibody Production

Applications to be received by 12pm on Thursday 9th of November 2017

Grade 8: £39,992 - £47,722 p.a.

A Postdoctoral Research Scientist in Protein and Antibody Production is required to join Professor Simon Draper’s blood-stage malaria vaccine development group at the Jenner Institute, University of Oxford. The research programme focuses on pre-clinical and clinical testing of novel blood-stage malaria vaccines and antibodies. You will be part of the preclinical vaccine development team and lead on the production and evaluation of new candidate protein vaccines and monoclonal antibodies (mAbs).

The position involves supporting and supervising the on-going programme of vaccine development within the blood-stage malaria group, with a particular emphasis on protein and mAb production. You will be responsible for driving the development of new technology platforms for new vaccine constructs and protein vaccines required for pre-clinical evaluation. You will be highly organised, motivated, and with significant proven experience in protein and mAb production and GMP process development.

You will have good interpersonal skills and be able to interact productively and accurately with other team members and external collaborators. Previous experience in protein or mAb production, good communication skills and the ability to work as part of a team are essential. The research will involve molecular biology, protein and mAb production and analysis, and sterile cell culture techniques.

Experience in GMP process development and a PhD (or near completion) in a relevant biological subject is essential.

If you are interested in this role, and have skills and experience we are looking for, please apply online.

Only applications received before 12.00 noon on 9 November 2017 will be considered.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here: www.ox.ac.uk/about/jobs/preemploymentscreening.

Contact: HR Officer - Recuitment (01865 617971)

To view a Job Description and apply

Clinical Research Fellow - Transmission-stage and Blood-stage Malaria Programmes

Applications to be received by 12pm on Thursday 30th of November 2017
Grade E64: £31,931 - £51,176 p.a.

THIS IS A RE-ADVERTISEMENT OF VACANCY ID 130181. PREVIOUS APPLICANTS NEED NOT APPLY.

We are seeking to appoint a Clinical Research Fellow to take an active role in the design and execution of clinical trials of investigational vaccines against malaria within the Transmission-Blocking and Blood-stage Malaria Vaccine Groups.

You will be responsible for clinical input into the trial design and execution, working closely with the clinical trials team, developing study protocols, ethical applications, advertising and recruitment, data management and analysis as well as screening and vaccination of volunteers. You will be highly organised and motivated.

You will have completed your Foundation Year 1 and 2 training and you will be fully GMC registered and permitted to practice medicine in the UK. You may have commenced or completed Core Medical Training or medical specialty equivalent. Holding a MRCP or MRCS would be an advantage.

You will have excellent communication skills, immaculate attention to detail, and good organisation and time management skills. You will have excellent interpersonal skills, including the ability to be comfortable and confident interacting with subjects and patients in a research study, including clinical research co-ordinators and other team members, laboratory and administrative staff, monitors, industry collaborators, clinical trial auditors and the broader research community. You should also be confident utilising IT and databases.

Previous laboratory and clinical trial experience, including ethics, GCP and documentation would be beneficial. Knowledge of immunology would be an advantage.

This post will provide invaluable experience for you if you are considering taking time out of clinical medicine to study for a higher degree. We are also offering you an excellent base from which you could apply for Training Fellowship funding.

The role requires some flexibility of working hours due to the nature of clinical trials.

Informal enquiries about this post can be addressed to: sumi.biswas@ndm.ox.ac.uk.

To apply, please complete an online application form and attach a copy of your CV and supporting statement.

Only applications received before 12.00 noon on 30 November 2017 will be considered.

Please note that the University of Oxford's retirement policy has changed. With effect from 1 October 2017, all employees at Grade 8 and above have a retirement age of the 30 September before the 69th birthday. All employees at Grades 1-7 do not have a set retirement age. Further details are available here: www.ox.ac.uk/about/jobs/preemploymentscreening.

Contact: HR Officer - Recruitment (01865 617971)

To view a Job Description and apply