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- The effect of tuberculin skin test and BCG vaccination on the expansion of PPD-specific IFN-γ producing cells ex vivo
- Mycobacterium tuberculosis PPD-induced immune biomarkers measurable in vitro following BCG vaccination of UK adolescents by multiplex bead array and intracellular cytokine staining
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Challenges in Developing a Controlled Human Tuberculosis Challenge Model.
Controlled human infection models (CHIMs) have provided pivotal scientific advancements, contributing to the licensure of new vaccines for many pathogens. ...
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HIV, HCMV and mycobacterial antibody levels: a cross‐sectional study in a rural Ugandan cohort
AbstractObjectivesA growing evidence base implicates human cytomegalovirus (HCMV) as a risk factor for TB disease. We investigated total IgG and ...
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Establishment of an Aerosol Challenge Model of Tuberculosis in Rhesus Macaques and an Evaluation of Endpoints for Vaccine Testing
ABSTRACT The establishment of an aerosol challenge model in nonhuman primates (NHPs) for the testing of vaccines against Mycobacterium tuberculosis would ...